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Boxplot of healthy control (HC), gastroesophageal reflux disease (GERD) phenotypes, and functional heartburn (FH). Bonferroni multiple comparison: *Mild ERD vs HC (P = 0.036), nonerosive reflux disease (NERD) (P = 0.004), and RH (P = 0.014). **Severe erosive reflux disease (ERD) vs HC (P = 0.002), NERD (P < 0.001), reflux hypersensitivity (RH) (P = 0.001), and FH (P = 0.004). Black lines inside the blue boxes show the median. Circles indicate outliers. IS, intercellular space.
