Table 2.
Subjects | HC | Mild ERD | Severe ERD | NERD | RH | FH |
---|---|---|---|---|---|---|
Sexa (n = 149) | n = 15 | n = 58 | n = 17 | n = 25 | n = 15 | n = 19 |
Male/female (69/80) | 2/13 | 30/28 | 11/6 | 13/12 | 4/11 | 9/10 |
Ageb (n = 149) | n = 15 | n = 58 | n = 17 | n = 25 | n = 15 | n = 19 |
43.4 ± 12.5 (mean ± SD, yr) | 38.8 ± 8.5 | 43.6 ± 11.7 | 52.8 ± 11.5 | 44.7 ± 15.1 | 39.1 ± 11.5 | 39.4 ± 11.1 |
Body mass indexc (n = 149) | n = 15 | n = 58 | n = 17 | n = 25 | n = 15 | n = 19 |
27.0 ± 4.9 (mean ± SD, kg/m2) | 23.9 ± 2.9 | 28.4 ± 5.2 | 28.8 ± 4.1 | 27.3 ± 4.7 | 24.8 ± 4.5 | 25.3 ± 4.2 |
MNBId (n = 140) (mean ± SD, Ω) | n = 15 | n = 51 | n = 15 | n = 25 | n = 15 | n = 19 |
2489.3 ± 529.1 | 1166.6 ± 726.0 | 428.5 ± 211.0 | 1235.8 ± 695.0 | 2120.3 ± 740.2 | 2228.3 ± 724.1 |
aPearson chi-square = 12.22, P = 0.032. Healthy control (HC) differs from severe erosive reflux disease (ERD).
bKruskal-Wallis H = 14.11, P = 0.015. Pairwise comparison: severe ERD vs HC (P = 0.041), vs functional heartburn (FH) (P = 0.028).
cKruskal-Wallis H = 24.53, P < 0.001. Pairwise comparison: severe ERD vs HC (P = 0.008), vs reflux hypersensitivity (RH) (P = 0.034). Mild ERD vs HC (P = 0.007), vs RH (P = 0.039).
dKruskal-Wallis H = 70.68, P < 0.001. Pairwise comparison: severe ERD vs HC (P < 0.001), vs mild ERD (P = 0.014), vs nonerosive reflux disease (NERD) (P = 0.008), vs RH (P < 0.001), vs FH (P < 0.001). Mild ERD vs HC (P < 0.001), vs severe ERD (P = 0.014), vs RH (P = 0.005), vs FH (P < 0.001). NERD vs HC (P = 0.001), vs FH (P = 0.020).
MNBI, mean nocturnal baseline impedance.