Table 3.

Significant Results of Group Difference (a) between the Bipolar Depressive Disorder (BDD) and Low Risk Major Depressive Disorder groups and (b) between the High Risk Major Depressive Disorder (MDD+) vs. Low Risk Major Depressive Disorder (MDD−) groups via GTG analysis.

(a)
Bipolar Depressive Disorder (BDD) vs. Low Risk Major Depressive Disorder (MDD−)
DWI measure	Region	Graph property	Corrected p-value	Cohen’d	BDD vs. MDD−
FA matrices	Right Middle Anterior Cingulate Gyrus and Sulcus	Communicability Efficiency	0.042	0.951	BDD > MDD−
TS matrices	Left Superior Frontal Gyrus	Communicability Efficiency	0.032	0.868	BDD > MDD−
(b)
High Risk Major Depressive Disorder (MDD+) vs. Low Risk Major Depressive Disorder (MDD−)
DWI measure	Region	Graph property	Corrected p-value	Cohen’d	MDD+ vs. MDD−
TS matrices	Left Middle Frontal Sulcus	Eigenvector Centrality	0.046	−0.920	MDD+ < MDD−

Abbreviations: GTG=Graph Theory GLM; BDD=Bipolar Depressive Disorder group; MDD+= High Risk Major Depressive Disorder; MDD−= Low Risk Major Depressive Disorder; FA=Fractional Anisotropy; TS= Total number of stream lines.