Transgender women/nonbinary people assigned male at birth	Transgender men/nonbinary people assigned female at birth	Implications for clinical practice
Breast cancer	Risk increased	Risk decreased	Mammography may be warranted for both groups Possible increased gender dysphoria from screening/treatment Be aware of barriers to screening/treatment
Cervical cancer	N/A	Risk may be increased; more research is needed	Follow current guidelines Possible increased gender dysphoria from pelvic examination Barriers to screening/treatment
Prostate cancer	Risk decreased	N/A	Follow current guidelines Be aware that estrogen may increase tumor aggressiveness Possible increased gender dysphoria from rectal examinations and treatment Barriers to screening/treatment
Testicular cancer	No change in risk	N/A	Possible gender dysphoria related to examinations Barriers to screening/treatment
Non‐reproductive cancers	More research is needed	More research is needed	Follow current guidelines as applicable Barriers to screening/treatment