TABLE 1.

MICs of MSI-78 for 10 S. aureus strains tested in different media and incubation conditions

Test medium	Incubation conditions	Geometric mean MIC (μg/ml)
MHa broth (unsupplemented)	Air	17.1
MH broth + 2–3% lysed horse blood	Air	34.3
MH broth + 2–3% lysed horse blood	5% CO2 in air	84.4
CAMHBb	Air	19.7
CAMHB + 2–3% lysed horse blood	Air	48.5
CAMHB + 2–3% lysed horse blood	5% CO2 in air	97.0
MH agar	Air	≥128
MH agar + 2–3% lysed horse blood	5% CO2 in air	≥128
CAMHB + 1% agarose	Air	0.32
CAMHB + 1% agarose	5% CO2 in air	1.52
CAMHB + 1% agarose + 2–3% lysed horse blood	5% CO2 in air	≥128
CAMHB + 1% agarose + HTMc supplements	5% CO2 in air	64
GC agar + XV supplementsd	5% CO2 in air	≥128
Wilkins-Chalgren agar	Anaerobic	≥128

^aMH, Mueller-Hinton. 

^bCAMHB, cation-adjusted Mueller-Hinton broth. 

^cHTM, haemophilus test medium. 

^dXV, defined supplement with hematin and NAD.