TABLE 2.

MICs of MSI-78 for 411 aerobic bacteria and rates of susceptibility to MSI-78 and eight other antibiotics

Microorganism	No.	MSI-78 MIC (μg/ml)a			% of isolates for which MSI-78 MICs were ≤64 μg/ml	% of isolates susceptible tob:
		50%	90%c	Range		OFLX	AMP	CFU	CFZ	CTAZ	CIP	GEN	PIP
Acinetobacter sp.	10	8	8	4–8	100	100	40	0	0	100	100	100	60
Alcaligenes faecalis	5	32		4–64	100	80	100	0	0	100	80	100	100
Citrobacter diversus	10	8	16	8–16	100	100	0	90	100	100	100	100	100
Citrobacter freundii	25	16	16	8–>256	96	92	16	72	4	92	100	100	96
Corynebacterium jeikeium	10	2	4	≤0.125–4	100	100	50	30	40	0	100	40	30
Enterobacter aerogenes	25	16	16	8–16	100	100	0	64	4	76	100	96	88
Enterobacter cloacae	25	16	32	1–128	96	100	8	32	4	76	100	100	84
Enterococcus faecalis	30	>256	>256	256–>256	0	83	100	0	0	0	87	0	100
Escherichia coli	30	8	16	8–16	100	97	67	97	93	100	97	97	67
Klebsiella oxytoca	10	16	16	8–16	100	100	0	100	40	100	100	100	90
Klebsiella pneumoniae	25	16	16	8–32	100	100	12	92	96	100	100	92	88
Pseudomonas aeruginosa	25	8	16	8–32	100	100	0	0	0	88	100	100	88
Pseudomonas fluorescens	5	8		2–8	100	100	0	0	0	100	100	100	100
Pseudomonas stutzeri	5	4		4–8	100	100	100	0	0	100	100	100	100
Staphylococcus aureus (MRSA)d	10	32	64	16–64	100	20	0	0	0	0	20	60	0
Staphylococcus aureus (MSSA)e	15	4	16	≤0.125–16	100	93	7	100	100	67	93	100	87
Staphylococcus epidermidis	25	4	8	≤0.125–8	100	100	0	100	100	88	100	100	88
Staphylococcus haemolyticus	10	4	8	4–8	100	100	0	10	10	0	20	100	0
Staphylococcus hominis	5	4		2–8	100	100	60	100	100	20	100	80	80
Staphylococcus simulans	5	0.5		≤0.125–2	100	100	100	100	100	80	100	100	100
Staphylococcus warneri	5	1		≤0.125–8	100	100	60	100	100	40	100	80	60
Staphylococcus xylosus	1			≤0.125	100	100	100	100	100	100	100	100	100
Stenotrophomonas maltophilia	10	8	16	4–16	100	70	20	0	0	50	50	0	30
Streptococcus agalactiae	25	16	32	16–32	100	92	100	100	100	100	100	0	100
Streptococcus bovis	5	16		8–16	100	20	0	100	100	100	100	80	0
Streptococcus equinus	2	2		2–16	100	0	0	100	50	50	50	50	0
Streptococcus pyogenes	30	16	32	16–256	97	97	100	100	100	100	100	0	100
Streptococcus group C	5	32		16–64	100	100	100	100	100	100	100	0	100
Streptococcus group G	5	16		16–64	100	80	100	100	100	100	100	0	100
Viridans group streptococci	13	32	>256	4–>256	85	39	77	100	100	85	69	31	77

^a50% and 90%, MICs at which 50 and 90% of the isolates are inhibited, respectively. 

^bAbbreviations (susceptibility breakpoints are in parentheses): OFLX, ofloxacin (≤2.0 μg/ml); AMP, ampicillin (≤8.0 μg/ml); CFU, cefuroxime (≤8.0 μg/ml); CFZ, cefazolin (≤8.0 μg/ml); CTAZ, ceftazidime (≤8.0 μg/ml); CIP, ciprofloxacin (≤1.0 μg/ml); GEN, gentamicin (≤4.0 μg/ml); PIP, piperacillin (≤16 μg/ml). 

^cMIC₉₀s were not calculated for species of which <10 strains were tested. 

^dMRSA, methicillin-resistant S. aureus. 

^eMSSA, methicillin-susceptible S. aureus.