Figure 1.

Antibacterial Resistance Leadership Group (ARLG) clinical studies of drug-resistant gram-negative bacterial infections. Abbreviations: ACUMIN, Acute Care Unit Minocycline; ARGONAUT, ARLG Reference Group for the Testing of Novel Therapeutics; COMBINE, Ceftazidime-Avibactam in Combination With Aztreonam; CRACKLE, Consortium on Resistance Against Carbapenems in Klebsiella and Other Enterobacterales; PHAGE, Study of the Safety and Microbiologic Activity of Bacteriophages; PHAT, Phages That Target MDR Bacteria; POP, Prospective Observational Pseudomonas Study; PROOF, Pharmacokinetics, Pharmacodynamics and Safety/Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adult Participants; SCENE, Screening for Colonization with Resistant Enterobacterales in Neutropenic Patients with Hematologic Malignancies; SHREC, Study of Highly Resistant Escherichia coli; SNAP, Study Network of Acinetobacter as a Carbapenem-Resistant Pathogen.