Table 1.
Univariate Analysis for Objective Response Rates in the High-AFP Group (n=77)
| Variables | Univariate | |
|---|---|---|
| OR (95% CI) | p-value | |
| Sex (male) | 0.857 (0.162–4.529) | 0.856 |
| Age (≥65 years) | 1.860 (0.475–7.293) | 0.373 |
| PS (1) | 1.083 (0.306–3.834) | 0.901 |
| ALBI grade (II) | 0.508 (0.175–1.474) | 0.213 |
| BCLC (C) | 0.629 (0.199–1.993) | 0.431 |
| Tumor size (mm) (≥50) | 0.900 (0.220–3.682) | 0.883 |
| Tumor number (multiple) | 0.464 (0.071–3.008) | 0.420 |
| Macrovascular invasion (yes) | 0.471 (0.150–1.483) | 0.198 |
| AFP (ng/mL) (≥400) | 1.493 (0.516–4.322) | 0.460 |
| AFP reduction >50% (yes) | 13.542 (3.991–45.950) | 0.000 |
Note: Bold values are statistically significant (p<0.05).
Abbreviations: OR, odds ratio; CI, confidence interval; PS, performance status; ALBI, albumin–bilirubin; BCLC, Barcelona Clinic Liver Cancer staging; AFP, alpha-fetoprotein.