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. 2023 Sep 8;10(5):869–883. doi: 10.3233/JND-230023

Table 1.

Baseline characteristics and sum-scores of 87 participants included in this study: 16 healthy controls, 20 recently diagnosed myasthenia gravis (MG) patients, 19 chronic MG patients, 14 seronegative MG (SNMG) patients, 6 chronic progressive external ophthalmoplegia (CPEO) patients, 6 oculopharyngeal muscular dystrophy (OPMD) patients and 6 Graves’ orbitopathy (GO) patients. Data are presented as number of patients (%) for categorical variables and as mean±SD for continuous variables. Synoptophore abnormalities is defined as having limited duction angles in any direction in one or both eyes. Hess-chart abnormalities is defined as having gaze deviations between the eyes above 5 degrees in any direction

MG Recently diagnosed n = 20 MG Chronic n = 19 MG Seronegative n = 14 CPEO n = 6 OPMD n = 6 GO n = 6 Healthy controls n = 16 p-value
Age (yrs) 59±19 51±16 57±9 49±14 62±10 44±12 54±13 0.243
Sex 0.754
Female 7 (35%) 9 (47%) 7 (50%) 3 (50%) 4 (67%) 4 (67%) 9 (56%)
Male 13 (65%) 10 (53%) 7 (50%) 3 (50%) 2 (33%) 2 (33%) 7 (44%)
Phenotype 0.105
Ocular 12 (60%) 6 (32%) 9 (64%) - - - -
Generalized 8 (40%) 13 (68%) 5 (36%) - - - -
Disease duration (months) 4.0±2.2 75.6±87.9 25.6±60.5 - - 22.8±35.9* - < 0.0001
MG-ADL 5.8±3.3 5.5±4.2 5.0±2.7 - - - - 0.791
MG-ADL (ocular items) 2.8±1.1 1.7±0.8 2.9±1.2 0.165
QMG 9.2±6.0 9.8±7.7 8.3±4.6 - - - - 0.812
QMG (ocular items) 2.2±0.7 1.2±0.7 2.5±1.0 0.365
Pyridostigmine on study day 25% 15% 14% - - - - 0.680
Hess-chart abnormalities 15 15 11 6 5 5 0
Synoptophore abnormalities 9 10 7 6 5 1 0
Ptosis at visit 10 5 5 5 5 0 0

*Two Graves’ orbitopathy patients were diagnosed longer than>one year ago and four patients<one year ago.