. 2023 Sep 8;13(6):999–1009. doi: 10.3233/JPD-230044

Table 3.

Annual decline in RWS recorded in PD and Oas and the difference in annual decline between PD and Oas across the study duration, from 18 months to 72 months

	Annual Decline of RWS		Difference in annual decline of RWS
WB duration (s)	OA (β, 95% CI, P, R²)	PD (β, 95% CI, P, R²)	(β, 95% CI, P, R²)

All >10	– 0.011, – 0.017, – 0.006 m/s,<0.001, 72%	– 0.021, – 0.037, – 0.004 m/s, 0.014, 55%	– 0.017, – 0.030, – 0.005 m/s, 0.006*, 39%
10 to 30	– 0.008, – 0.013, – 0.003 m/s, 0.001, 69%	– 0.013, – 0.020, – 0.006 m/s,<0.001, 71%	– 0.007, – 0.013, – 0.000 m/s, 0.036*, 67%
30 to 60	– 0.009, – 0.015, – 0.004 m/s, 0.001, 61%	– 0.014, – 0.021, – 0.008 m/s,<0.001, 76%	– 0.007, – 0.014, – 0.001 m/s, 0.035*, 64%
>60	– 0.013, – 0.021, – 0.005 m/s, 0.001, 73%	– 0.004, – 0.014, 0.006 m/s, 0.466, 71%	– 0.000, (– 0.011, 0.011 m/s, 0.938, 69%)

PD, Parkinson’s disease; OA, older adults; RWS, real-world walking speed; WB, walking bout. Estimated from a mixed linear regression model including 186 RWS measures from 85 PD participants and 240 RWS measures from 111 OA participants with age, sex and HY stage (in PD only), as covariates. Subject also a random effect to account for the correlation of measures of the same subject and a interaction term between follow up time (in years) and group (PD or OA). ‘*” – indicates significant difference in annual decline of RWS between PD and OAs.