Baicalin
|
ERK, ROS ↓ |
Neurodegenerative disorder diseases |
Behavioral deficits ↓ |
Embolic stroke in rabbits; AIS |
PPAR-γ expression ,translocation ↓ |
Ischemia-reperfusion injury |
VEGF ↓ |
Angiogenesis of prostate cancer |
PD146176
|
Plasma 12-HETE ↓ |
Vascular calcification |
EMT ↓ |
ECRS with nasal polyps |
Inflammation, fibrosis, macrophages infiltration ↓ |
UUO treatment of Alox15 knockout mice |
BHPP
|
Urinary 12-HETE,12-HETE/cr excretion ↓ |
DKD |
NDGA
|
Oxidative stress index ↓ |
DKD |
ML351
|
Glutamate oxidative toxicity ↓ |
Ischemic stroke |
ML355
|
PAR-4 -induced aggregation, calcium mobilization, 12-HETE in β-cells ↓ |
DM; Anti-platelet therapy |