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. Author manuscript; available in PMC: 2024 Feb 3.
Published in final edited form as: Eur Respir J. 2023 Aug 3;62(2):2300502. doi: 10.1183/13993003.00502-2023

Figure 3. Association of nasal airway DEmiRNAs in infants with bronchiolitis with asthma-related clinical variables.

Figure 3.

A. Association between the DEmiRNAs or non-DEmiRNAs and that of 16 asthma-related clinical variables in infants with severe bronchiolitis. The red web denotes the average effect estimates of the aggregated DEmiRNAs for the 16 clinical variables. The green web denotes the average effect estimates of the aggregated non-DEmiRNAs for the 16 clinical variables. B. The relationship of the 23 DEmiRNAs with the 16 asthma-related clinical variables was examined by the DESeq2 negative binomial generalized linear model adjusting for age and sex. The blue-to-red gradient in the heatmap denotes the magnitude and direction of the associations. The size of the dot denotes the magnitude of the associations. Abbreviations: FDR, false discovery rate; IgE, immunoglobulin E; PPV, positive pressure ventilation; RSV, respiratory syncytial virus; RSV-A, respiratory syncytial virus A; RSV-B, respiratory syncytial virus B; RV, rhinovirus; RV-A, rhinovirus A; RV-B, rhinovirus B; RV-C, rhinovirus C.