. 2023 Sep 26;66(19):13556–13567. doi: 10.1021/acs.jmedchem.3c00852

Table 3. In Vitro Characterization of 10–12 Derived from Screening Hit 5o and 5o/AQ-Hybrid 13^a.

Binding affinity to the Nurr1 LBD was determined by ITC. Nurr1 modulation was determined in the Gal4–Nurr1 hybrid reporter gene assay; data are mean ± SD; n ≥ 3.

Table 3. In Vitro Characterization of 10–12 Derived from Screening Hit 5o and 5o/AQ-Hybrid 13a.

Table 3. In Vitro Characterization of 10–12 Derived from Screening Hit 5o and 5o/AQ-Hybrid 13^a.