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. 2023 Oct 16;18(10):e0293040. doi: 10.1371/journal.pone.0293040

Table 4. Relationships between survey outcomes and annual hormone Area Under the Curve Relative to Increase (AUCI).

Females Males
AUCI for E2 AUCI for T AUCI for E2 AUCI for T
Beta p-value* Beta p-value* Beta p-value* Beta p-value*
SMFQ -0.029 0.17 -0.015 0.28 0.025 0.45 0.003 0.17
YSR total psychopathology -0.293 0.001 -0.156 0.01 0.178 0.35 -0.005 0.69
YSR anxious/depressed -0.182 0.002 -0.088 0.03 0.051 0.69 -0.003 0.74
YSR withdrawn/depressed -0.124 0.04 -0.061 0.13 0.138 0.27 -0.001 0.89
YSR somatic complaints 0.095 0.11 -0.073 0.06 0.126 0.36 0.004 0.72
YSR social problems -0.132 0.03 -0.084 0.03 0.084 0.46 0.009 0.24
YSR thought problems -0.100 0.09 -0.085 0.03 0.040 0.75 -0.004 0.67
YSR attention problems -0.119 0.03 -0.066 0.06 0.028 0.81 -0.012 0.14
YSR rule-breaking behaviours -0.096 0.04 -0.053 0.09 -0.030 0.79 -0.005 0.57
YSR aggressive behaviours -0.111 0.02 -0.035 0.24 -0.023 0.84 -0.008 0.30
YSR self-harm -0.001 0.28 -0.001 0.10 -0.001 0.77 -0.0001 0.53
YSR suicidal ideation -0.003 0.07 -0.001 0.20 0.002 0.48 -0.0001 0.73
Impulsive-aggression -0.021 0.02 -0.007 0.24 0.015 0.43 -0.0002 0.89
Sleep–weekday (hr) 0.008 0.11 0.003 0.40 -0.008 0.50 -0.001 0.34
Sleep—weekend (hr) 0.007 0.25 0.007 0.12 -0.047 0.01 -0.001 0.43
Self-harm -0.001 0.27 -0.001 <0.001 -0.0002 0.72 0.00002 0.70

*p-value is from a linear mixed regression model assessing the relationship between survey outcomes and hormone AUCI, separately by sex and hormone. Boldface indicates a significant (p<0.033) relationship.