TABLE 4.
Outcome in microbiologically documented infections in evaluable patients
Type of infection | No. of patients (%) treated witha:
|
|||
---|---|---|---|---|
Meropenem
|
Cefuroxime-gentamicin (±metronidazole)
|
|||
Treatment | Eradication | Treatment | Eradication | |
Bacteriologically documented | 22 (60) | 19 (58) | ||
With bacterium-positive blood culture | 9 (24) | 9 (27) | ||
Pneumoniab | 12 | 10 (83) | 13 | 1 (69) |
Gram-positive | ||||
Staphylococcus aureus | 6 [1]c | 2 [1] | ||
Streptococcus pneumoniae | 3 | 1 [1] | ||
Streptococcus spp. | 2 [1] | 3 | ||
Other | 8 | 1 | ||
Gram-negative | ||||
Enterobacteriaceae | 24 [5] | 30 [6] | ||
Pseudomonas spp. | 2 | 0 | ||
Other | 1 | |||
Anaerobic | 4 [2]d | 2 [1]e | ||
Total | 37 | 15/22 (68) | 33 | 12/19 (63) |
No significant difference in bacteriological outcome between the groups (P = 0.75; 95% CI, −24 to 34%).
No significant difference in bacteriological outcome between the groups.
Figures in brackets denote numbers of bacterium-positive blood cultures.
Blood cultures positive for Bacteroides spp.
Blood cultures positive for Bacteroides fragilis.