Table 3.
Sensitivities and specificities for candidate criteria for unassisted fistula maturation
| Time Frame | 3 mo | 4 mo | 5 mo | 6 mo | 9 mo | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Performance Characteristic | Sens. | Spec. | AUC (95% CI) | Sens. | Spec. | AUC (95% CI) | Sens. | Spec. | AUC (95% CI) | Sens. | Spec. | AUC (95% CI) | Sens. | Spec. | AUC (95% CI) |
| % (95% CI) TP/(TP+FN) |
% (95% CI) TN/(TN+FP) |
% (95% CI) TP/(TP+FN) |
% (95% CI) TN/(TN+FP) |
% (95% CI) TP/(TP+FN) |
% (95% CI) TN/(TN+FP) |
% (95% CI) TP/(TP+FN) |
% (95% CI) TN/(TN+FP) |
% (95% CI) TP/(TP+FN) |
% (95% CI) TN/(TN+FP) |
||||||
| HFM | 61 (55 to 66) 179/296 |
100 (99 to 100) 239/239 |
0.80 (0.77 to 0.83) | 79 (74 to 84) 234/296 |
100 (99 to 100) 239/239 |
0.90 (0.87 to 0.92) | 90 (86 to 93) 234/296 |
100 (98 to 100) 239/239 |
0.95 (0.93 to 0.97) | 94 (90 to 96) 234/296 |
100 (99 to 100) 239/239 |
0.97 (0.95 to 0.98) | Ref | Ref | Ref |
| NAVAC | 63 (57 to 68) 186/296 |
96 (93 to 98) 230/239 |
0.80 (0.77 to 0.83) | 76 (70 to 81) 224/296 |
95 (92 to 98) 228/239 |
0.86 (0.83 to 0.88) | 84 (80 to 88) 249/296 |
95 (91 to 97) 227/239 |
0.90 (0.87 to 0.92) | 86 (81 to 90) 254/296 |
95 (91 to 97) 227/239 |
0.90 (0.88 to 0.93) | 90 (86 to 93) 267/296 |
94 (90 to 97) 225/239 |
0.92 (0.90 to 0.94) |
| KHI | 75 (69 to 80) 221/296 |
88 (83 to 92) 210/239 |
0.81 (0.78 to 0.8) | 86 (81 to 88) 253/296 |
86 (81 to 90) 206/239 |
0.86 (0.83 to 0.89) | 94 (91 to 97) 279/296 |
86 (81 to 90) 206/239 |
0.90 (0.88 to 0.93) | 97 (94 to 99) 287/296 |
86 (81 to 90) 206/239 |
0.92 (0.89 to 0.94) | 100 (99 to 100) 296/296 |
85 (80 to 89) 203/239 |
0.92 (0.90 to 0.95) |
| No use of alternative vascular access for ≥1 mo | 62 (56 to 68) 184/296 |
96 (92 to 98) 229/239 |
0.79 (0.76 to 0.82) | 78 (73 to 83) 232/296 |
95 (92 to 98) 228/239 |
0.87 (0.84 to 0.90) | 89 (85 to 92) 263/296 |
95 (92 to 98) 228/239 |
0.92 (0.90 to 0.94) | 93 (89 to 95) 274/296 |
95 (92 to 98) 228/239 |
0.94 (0.92 to 0.96) | 97 (94 to 99) 287/296 |
95 (91 to 97) 226/239 |
0.96 (0.94 to 0.98) |
| Four consecutive uses of fistula with BPS ≥300 ml/min | 57 (51 to 63) 168/296 |
98 (96 to 100) 235/239 |
0.78 (0.75 to 0.80) | 74 (69 to 79) 220/296 |
98 (95 to 99) 234/239 |
0.86 (0.83 to 0.89) | 85 (81 to 89) 252/296 |
98 (95 to 99) 234/239 |
0.92 (0.89 to 0.94) | 88 (84 to 92) 261/296 |
98 (95 to 99) 234/239 |
0.93 (0.91 to 0.95) | 93 (90 to 96) 277/296 |
98 (95 to 99) 233/239 |
0.96 (0.94 to 0.97) |
| Four consecutive uses of fistula | 73 (67 to 78) 215/296 |
95 (92 to 98) 228/239 |
0.84 (0.81 to 0.87) | 86 (82 to 90) 255/296 |
94 (90 to 96) 224/239 |
0.90 (0.87 to 0.92) | 93 (89 to 96) 275/296 |
94 (90 to 96) 224/239 |
0.93 (0.91 to 0.95) | 97 (94 to 99) 287/296 |
94 (90 to 96) 224/239 |
0.95 (0.94 to 0.97) | 100 (98 to 100) 295/296 |
92 (87 to 95) 219/239 |
0.96 (0.94 to 0.97) |
| ≥1 use of fistula | 78 (73 to 83) 231/296 |
93 (88 to 96) 221/239 |
0.85 (0.82 to 0.88) | 89 (85 to 92) 263/296 |
90 (85 to 94) 215/239 |
0.89 (0.87 to 0.92) | 95 (91 to 97) 280/296 |
89 (84 to 92) 212/239 |
0.92 (0.89 to 0.94) | 98 (95 to 99) 289/296 |
88 (84 to 92) 211/239 |
0.93 (0.91 to 0.95) | 100 (99 to 10) 296/296 |
86 (81 to 90) 205/239 |
0.93 (0.91 to 0.95) |
Sens., sensitivity; Spec., specificity; CI, confidence interval; TP, true positive; FN, false negative; TN, true negative; FN, false positive; AUC, area under the curve; HFM, Hemodialysis Fistula Maturation; Ref, reference; NAVAC, North America Vascular Access Consortium; KHI, Kidney Health Initiative; BPS, blood pump speed.