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. 2023 Oct 13;102(41):e34885. doi: 10.1097/MD.0000000000034885

Table 5.

Comparison of demographic characteristics health-related outcomes between Class 1 and Class 2 participants.

Variable Total (n = 172) Class 1 (n = 66) Class 2 (n = 106) P value FDR*
Demographics
 Gender, n (%)
  Female 108 (62.7) 35 (53.0) 73 (68.8) .036 0.094
  Male 64 (37.2) 31 (46.9) 33 (31.1)
 Age, years, mean (SD) 58.7 (10.6) 61.5 (11.0) 57.0 (10.1) .009 0.036
 Ethnicity, n (%)
  Hispanic or Latino 8 (4.8) 2 (3.2) 6 (5.8) .451 0.0.601
  Not Hispanic or Latino 157 (95.1) 60 (96.8) 97 (94.2)
 Race, n (%)
  Black/African American 9 (5.4) 3 (4.7) 6 (5.8) .392 0.565
  White 150 (90.4) 59 (93.6) 91 (88.3)
  Other 7 (4.2) 1 (1.5) 6 (5.8)
 Education, n (%)
  No high school diploma 3 (1.7) 2 (3.0) 1 (.94) .743 0.787
  High school graduate or GED 19 (11.0) 8 (12.1) 11 (10.4)
  Some college, no degree 34 (19.7) 14 (21.2) 20 (18.8)
  Occupational/technical/vocational program 9 (5.2) 2 (3.0) 7 (6.6)
  Associate degree: academic program 27 (15.7) 7 (10.6) 20 (18.8)
  Bachelor’s degree 41 (23.8) 16 (24.2) 25 (23.5)
  Master’s degree 29 (16.8) 13 (19.7) 16 (15.1)
  Professional school degree 4 (2.3) 1 (1.5) 3 (2.8)
  Doctoral degree 6 (3.5) 3 (4.5) 3 (2.8)
 Employment, n (%)
  Working now 32 (18.6) 11 (16.6) 21 (19.8) .748 0.787
  Unemployed 5 (2.9) 2 (3.0) 3 (2.8)
  Disabled 27 (15.57) 9 (13.6) 18 (16.9)
   Disabled due to back pain 61 (35.4) 22 (33.3) 39 (36.7)
  Retired 36 (20.9) 18 (27.2) 18 (16.9)
  Other (includes Other, Sick or maternity leave, Student, Keeping house) 11 (6.4) 4 (6.0) 7 (6.6)
Back pain history and perception characteristics (NIH MD)
 CLBP duration, n (%)
  3–6 months 1 (0.6) 0 (0.0) 1 (.94) .717 0.787
  6 months–1 year 4 (2.3) 2 (3.0) 2 (1.8)
  1–5 years 25 (14.5) 8 (12.1) 17 (16.0)
  >5 years 142 (82.6) 56 (84.5) 86 (81.1)
 Prior treatments for back pain, Yes, n (%)
  Injections (e.g., epidural steroid, facet) 140 (81.4) 50 (75.7) 90 (84.9) .188 0.358
  Exercise therapy (physical therapy) 160 (93.0) 61 (92.4) 99 (93.4) .402 0.565
  Psychological counseling 62 (36.0) 24 (36.4) 38 (35.8) .966 0.966
 History of a low back operation, n (%)
  Yes 51 (59.3) 20 (54.0) 31 (63.2) .682 0.787
   One operation 32 (18.6) 16 (24.2) 16 (15.1)
   More than one operation 54 (31.4) 21 (31.8) 33 (31.1) .376 0.563
  No 85 (49.4) 29 (43.9) 56 (52.8)
 I feel that my back pain is terrible and it’s never going to get any better…, n (%)
  Agree 82 (47.6) 28 (42.4) 54 (50.9) .038 0.094
  Disagree 81 (47.1) 31 (46.9) 50 (47.2)
 It’s not really safe for a person with my back problem to be physically active…, n (%)
  Agree 60 (34.8) 21 (31.8) 39 (36.7) .654 0.787
  Disagree 108 (62.7) 44 (66.6) 64 (60.4)
Clinical characteristics
 Average pain severity (BPI, 0–10 score), mean (SD) 5.9 (1.5) 5.7 (1.6) 6.0 (1.4) .126 0.252
 Function
  Pain interference (BPI, 0–10 score range), mean (SD) 6.4 (1.9) 5.9 (2.0) 6.7 (1.7) .012 0.042
  Back pain-related disability (ODI, 0–100 score range), mean (SD) 47.4 (13.6) 46.1 (14.5) 49.5 (12.9) .109 0.236
 Health-related quality of life (SF-12)
  Physical health composite score (0–100 range), mean (SD) 28.2 (8.6) 27.9 (9.2) 28.3 (8.3) .723 0.787
  Mental health composite score (0–100 range), mean (SD) 43.7 (11.4) 48.1 (10.5) 40.9 (11.1) <.001 0.005
 Daily dose of prescribed opioids, past 14 days (TLFB, morphine-equivalent mg/day), average daily dose, mean (SD) 196.2 (786.1) 227.7 (819.3) 176.6 (768.1) .679 0.787
 Opioid misuse risk (COMM), total score (0-35 range), mean (SD) 8.9 (6.2) 6.8 (4.6) 10.3 (6.6) <.001 0.005
 Sleep quality (NIH MD), total score (4-19 range), mean (SD) 10.1 (3.8) 10.6 (3.7) 9.8 (3.8) .193 0.358
 Negative affect (HADS), total score (1-36 range), mean (SD) 16.2 (7.7) 13.7 (7.8) 17.7 (7.2) <.001 0.005
 Pain catastrophizing (PCS), total score (0-50 range), mean (SD) 19.4 (11.5) 16.6 (10.5) 21.2 (11.8) .010 0.037
 Loneliness (UCLA LS), total score (3-9 range), mean (SD) 5.7 (2.1) 5.3 (2.2) 6.0 (2.1) .034 0.093
 Feeling loved (FLI)
  Feeling loved by others (0-100 score range), mean (SD) 80.1 (21.7) 82.0 (21.0) 78.9 (22.1) .362 0.563
  Loving yourself (0-100 score range), mean (SD) 69.7 (27.8) 75.1 (23.6) 66.3 (29.8) .049 0.116
Healthcare utilization and productivity characteristics (past 6 months)
 Hospitalized, Yes, # (%) 27 (15.8) 6 (9.2) 21 (19.8) .118 0.245
  Number of nights hospitalized (n = 27), mean (SD) 10.5 (18.7) 8.8 (14.0) 11.0 (20.1) .808 0.824
 ED visit, Yes, # (%) 47 (27.5) 14 (21.5) 33 (31.1) .252 0.437
  Number of ED visits (n = 47), mean (SD) 2.5 (3.1) 1.6 (0.9) 3.0 (3.6) .218 0.391
 Clinic visit (“regular” care, urgent care), Yes, # (%) 148 (87.5) 55 (84.4) 93 (89.4) .336 0.549
  Number of clinic visits (n = 148), mean (SD) 7.6 (9.6) 6.6 (6.0) 8.0 (11.1) .379 0.563
 Mental health care visit, Yes, # (%) 61 (35.9) 19 (27.7) 42 (40.4) .093 0.210
  Number of mental health care visits (n = 61), mean (SD) 9.7 (8.5) 10.8 (10.3) 8.9 (7.5) .434 0.594
 Addiction care visit, Yes, # (%) 6 (3.5) 3 (4.6) 3 (2.8) .546 0.693
  Number of addiction care visits (n = 6), number, mean (SD) 11.8 (20.3) 3.0 (2.6) 20.7 (28.0) .338 0.549
 Whole workdays missed (among those “working now”), Yes, # (%) 35 (27.3) 12 (18.5) 23 (21.7) .469 0.610
  Number of whole workdays missed (n = 35), mean (SD) 47.2 (63.4) 54.7 (66.7) 43.3 (62.7) .623 0.771
 Chores (school/house work) missed, Yes, # (%) 121 (78.5) 41 (61.5) 80 (75.5) .026 0.075
  Number of whole days of chores missed (n = 121), mean (SD) 45.1 (49.8) 44.7 (56.3) 44.5 (46.6) .757 0.787

BPI = Brief Pain Inventory, CLBP = Chronic Low Back Pain, COMM = Current Opioid Misuse Measure, ED = Emergency Department, FDR = False Discovery Rate, FLI = Feeling Loved Instrument, HADS = Hospital Anxiety Depression Scale, HCUPS = HealthCare Utilization and Productivity Survey, NIH MD = NIH Minimal Data Set, PCS = Pain Catastrophizing Scale, SF-12 = 12-Item Short Form Health Survey, TLFB = Timeline Followback, UCLA LS = UCLA Loneliness Scale.

*

False Discovery Rate (P value corrected for multiple comparisons).