TABLE 1.
Demographic and clinical characteristics of study participants
| HC (N = 29) | HD (N = 10) | mAH (N = 16) | sAH (N = 40) | AC (N = 10) | |
|---|---|---|---|---|---|
| Age | |||||
| Mean | 46.28 | 44.50 | 48.06 | 44.88 | 49.30 |
| Range | 23–66 | 29–63 | 26–60 | 25 65 | 35–66 |
| Sex, n (%) | |||||
| Female | 18 (62.1) | 5 (50.0) | 8 (50.0) | 17 (42.5) | 5 (50.0) |
| Male | 11 (37.9) | 5 (50.0) | 8 (50.0) | 23 (57.5) | 5 (50.0) |
| Race, n (%) | |||||
| Black | 5 (16.7) | 5 (50.0) | 1 (16.2) | 2 (5.0) | 1 (10.0) |
| Asian | 2 (6.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Hispanic | 1 (3.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Unknown | 4 (13.3) | 1 (10.0) | 0 (0.0) | 1 (2.5) | 0 (0.0) |
| White | 18 (60.0) | 4 (40.0) | 15 (93.8) | 37 (92.5.0) | 9 (90.0) |
| MELD | |||||
| Mean (SE) | NA | NA | 14.07 (1.36) | 26.08 (1.60) | 14.00 (2.79) |
| AST | |||||
| Mean (SE) | 20.79 (1.63) | 25.90 (2.04) | 103.31 (18.95) | 136.98 (11.35) | 46.30 (6.82) |
| ALT | |||||
| Mean (SE) | 20.95 (2.01) | 24.00 (4.28) | 57.75 (13.23) | 44.25 (3.76) | 26.40 (4.04) |
| Albumin | |||||
| Mean (SE) | 4.34 (0.04) | 3.97 (0.11) | 2.89 (0.21) | 2.53 (0.07) | 3.34 (0.32) |
| Creatinine | |||||
| Mean (SE) | 0.88 (0.05) | 0.95 (0.11) | 0.72 (0.06) | 0.93 (0.09) | 1.09 (0.23) |
| Bilirubin | |||||
| Mean (SE) | 0.59 (0.07) | 0.72 (0.09) | 5.12 (1.12) | 21.42 (1.17) | 5.03 (2.79) |
| INR | |||||
| Mean (SE) | 1.03 (0.02) | 1.01 (0.03) | 1.25 (0.06) | 1.96 (0.06) | 1.38 (0.10) |
| Child-Pugh Score | |||||
| Mean (SE) | NA | NA | 8.57 (0.43) | 10.75 (0.21) | 8.00 (0.65) |
Abbreviations: AC, alcohol-associated cirrhosis; HC, healthy control; HD, heavy drinker; mAH, moderate alcohol-associated hepatitis; sAH, severe alcohol-associated hepatitis.