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. 2022 Aug 25;49:e20223341. doi: 10.1590/0100-6991e-20223341-en

Table 2. Data regarding treatment and follow-up of patients diagnosed with sacrococcygeal teratoma treated surgically from 2004 to 2019, compared by reference center.

Variables Reference center for fetal and obstetric risk n=18 n(%) Reference cancer center n=7 n(%) p-value
Surgical approach Perineal 17 (94.4%) 6 (85.7%) 0.920
Abdominal-Perineal 1 (5.6%) 1 (14.3%)
Histopathological Report Mature Teratoma 13 (72.2%) 2 (28.6%) 0.007
Immature Teratoma 1 (5.6%) 0 (0.0%)
Malignant Teratoma* 4 (22.2%) 5 (71.4%)
Adjuvant Chemotherapy Yes 0 (0.0%) 2 (28.6%) 0.123
Post-surgery Complications No Complications 10 (55.6%) 2 (28.6%) 0.078
Infection 0 (0.0%) 1 (14.3%)
Dehiscence) 4 (22.2%) 0 (0.0%)
Infection + Dehiscence 4 (22.2%) 4 (57.1%)
Alpha-fetoprotein (AFP) Post-Surgery Not Altered 15 (83.3%) 6 (85.7%) 0.647
Altered 3 (16.7%) 1 (14.3%)
Rectal exam Normal 5 (27.8%) 7 (100.0%) 0.005
Not Performed 13 (72.2%) 0 (0.0%)
Post-surgery Tests USG 12 (66.6%) 3 (42.9%) 0.004
CT 3 (16.7%) 0 (0.0%)
CT + USG 0 (0.0%) 4 (57.1%)
Not Performed 3 (16.7%) 0 (0.0%)
Surgery Sequelae Yes1,2 4 (22.2%) 2 (28.6%) 0.644
No 12 (66.7%) 5 (71.4%)
No Information 2 (11.1%) 0 (0.0%)
Outcome Alive without disease 6 (33.3%) 4 (57.1%) 0.022
Alive with disease 0 (0.0%) 1 (14.3%)
Referred to another hospital 1 (5.6%) 0 (0.0%)
Loss of follow-up 5 (27.8%) 0 (0.0%)
Outpatient discharge 6 (33.3%) 0 (0.0%)
Death** 0 (0.0%) 2 (28.6%)

CT: computed tomography; MR: magnetic resonance; USG: ultrasound. 1Reference center for fetal and obstetric risk: Sacral Dimple (3); PilonidalCyst (1); Myelomeningocele (2); SpinaBifida (1). 2Reference cancer center: Sacral Dimple (1); Meningocele (1).