Table 2. Clinical characteristics of the patients before the use of extracorporeal membrane oxygenation (N = 30).a .
Characteristic | Result |
---|---|
Time to ECMO, days | |
First symptoms to ECMO | 19 [13-24] |
Hospital admission to ECMO | 11 [5-15] |
Intubation to ECMO | 4 [1-10] |
Total SOFA scoreb | 11 [8-12] |
Vasoactive-inotropic scoreb | 6 [0-25] |
APPSb | 7 [7-8] |
RESP scoreb | 2 [2-5] |
Murray score | 3.3 [3.3-3.5] |
Ventilation parameters | |
Fio2, %b | 100 [100-100] |
PEEP, cmH2Ob | 10 [10-10] |
RR, breaths/min | 34 [30-36] |
Plateau pressure, cmH2Oc | 28.5 [25-32] |
Driving pressure, cmH2Oc | 17 [13-24] |
Pulmonary compliance, cmH2Oc | 20 [15-24] |
Laboratory analysis | |
pHb | 7.31 [7.23-7.40] |
Pao2/Fio2 b | 66 [54-75] |
pCo2, mmHgb | 55 [47-68] |
Plasma bicarbonate, mmol/Le | 27 [22-32] |
Arterial lactate, mg/dL | 14 [11-20] |
White cell count, cells/mm³c | 12.920 [9.510-15.300] |
Lymphocytes, cells/mm³c | 680 [550-990] |
Serum creatinine, mg/dLc | 0.90 [0.57-1.36] |
Rescue therapy before ECMO | |
Neuromuscular blockade, hd,f | 48 [5-144] |
Prone positioning | 23 (76.7) |
Inhaled nitric oxide | 01 (3.3) |
ECMO: extracorporeal membrane oxygenation; APPS: acronym for Age, Pao2/FIo2 ratio, and Plateau pressure measured at 24 h after diagnosis of ARDS Score; and RESP: Respiratory ECMO Survival Prediction score. aValues expressed as n (%) or median [IQR]. bn = 29. n = 28. dn = 27. en = 24. fAll patients used neuromuscular blockers, but only 27 patients had the total number of hours of treatment recorded.