Table 2.
Comparison of the same stimulus effect on MK and PTN production between different cells.
Cytokine | Monocytes | Macrophages | MDDCs | MDCs | PDCs | p-Value | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mo/Ma | Mo/MDDC | Mo/MDC | Mo/PDC | Ma/MDDC | Ma/MDC | Ma/PDC | MDDC/MDC | MDDC/PDC | MDC/PDC | ||||||
LPS | |||||||||||||||
MK | 68.6 | 125.2 | 184.8 | 0 | – | 0.48 | 0.29 | 0.021 | – | 0.57 | 0.004 | – | 0.14 | – | – |
PTN | 207.7 | 267.7 | 311.7 | 205.3 | – | 0.034 | 0.0009 | 0.8389 | – | 0.1 | 0.03 | – | 0.001 | – | – |
Poly I:C | |||||||||||||||
MK | 12.7 | 1.1 | 6.8 | 0 | – | 0.017 | 0.55 | 0.0434 | – | 0.52 | 0.4 | – | 0.42 | – | – |
PTN | 179.3 | 226.7 | 311 | 184.7 | – | 0.03 | 0.004 | 0.6875 | – | 0.071 | 0.007 | – | 0.005 | – | – |
Resquimod | |||||||||||||||
MK | 24.5 | 1.1 | 21.3 | 0 | 29.4 | 0.001 | 0.61 | 0.0115 | 0.6 | 0.005 | 0.4 | 0.013 | 0.026 | 0.96 | 0.046 |
PTN | 206.3 | 284.7 | 313.7 | 183.0 | 159.3 | 0.004 | 0.001 | 0.3354 | 0.035 | 0.062 | 0.001 | 0.001 | 0.0007 | 0.0006 | 0.2 |
CpG DNA | |||||||||||||||
MK | 5.5 | 0 | 4.9 | 0 | 15.8 | 0.006 | 0.930 | 0.034 | 0.024 | 0.42 | – | 0.004 | 0.42 | 0.2 | 0.029 |
PTN | 215.3 | 282.3 | 340 | 191.3 | 155.7 | 0.047 | 0.002 | 0.2539 | 0.01 | 0.09 | 0.026 | 0.006 | 0.002 | 0.0002 | 0.151 |
Mo, monocytes and Ma, macrophages. The standard deviation (S.D.) values for the average levels in this table are the same in Table 1.