Table 1.

Literature search criteria used

Database	From the period of inception to 9th October 2022 with keywords	Results
MEDLINE (PubMed)	(((“indigenous peoples”[MeSH Terms] OR (“indigenous”[All Fields] AND “peoples”[All Fields]) OR “indigenous peoples”[All Fields] OR “natives”[All Fields] OR “native”[All Fields] OR “natives”[All Fields] OR “natively”[All Fields] OR “nativeness”[All Fields] OR “nativity”[All Fields]) AND (“collagen type ii”[MeSH Terms] OR (“collagen”[All Fields] AND “type”[All Fields] AND “II”[All Fields]) OR “collagen type ii”[All Fields] OR (“type”[All Fields] AND “II”[All Fields] AND “collagen”[All Fields]) OR “type ii collagen”[All Fields])) OR ((“undenaturated”[All Fields] OR “undenatured”[All Fields]) AND (“collagen type ii”[MeSH Terms] OR (“collagen”[All Fields] AND “type”[All Fields] AND “II”[All Fields]) OR “collagen type ii”[All Fields] OR (“type”[All Fields] AND “II”[All Fields] AND “collagen”[All Fields]) OR “type ii collagen”[All Fields])) OR (“UC”[All Fields] AND “II”[All Fields])) AND (“osteoarthritis, knee”[MeSH Terms] OR (“osteoarthritis”[All Fields] AND “knee”[All Fields]) OR “knee osteoarthritis”[All Fields] OR (“knee”[All Fields] AND “osteoarthritis”[All Fields]))	56
Embase	(native AND type AND ii AND collagen OR (undenatured AND type AND ii AND collagen) OR ‘uc ii’) AND ‘knee osteoarthritis’	20
Scopus	(ALL (undenatured AND type AND ii AND collagen) OR ALL (uc-ii) AND ALL (knee AND osteoarthritis))	185
Cochrane Library	Undenatured type II collagen in All Text OR i UC-II* in All Text OR Native Type II Collagen in All Text AND knee osteoarthritis in All Text - with Publication Year from 2000 to 2022, in Trials (Word variations have been searched)	32
Total		293