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. 2023 Sep 20;54(5):978–984. [Article in Chinese] doi: 10.12182/20230960503

表 2. Associations of adulthood BMI with the concentration of obesity-related breast cancer risk biomarkers.

成年后期BMI与肥胖相关乳腺癌风险标志物浓度的关联

Model Adiponectin Resistin C-reactive protein Insulin-like growth
factor binding protein-3
Soluble leptin receptor
β (95% CI) P β (95% CI) P β (95% CI) P β (95% CI) P β (95% CI) P
 # Low weight group (n=7) was not included in this analysis. Model 1 was adjusted for age at enrollment (continuous); Model 2 was adjusted for age at enrollment (continuous), highest education attained (primary school or lower, primary and junior high school, and senior high school and college), occupation (administration; manufacturing, construction, service, business, and farming; unemployed, retired and others), age of menarche (<14 or ≥14 years old), menopause status (premenopausal or postmenopausal), history of livebirth(s) (yes or no), smoking (yes or no) and drinking (yes or no).
Model 1#
 Normal weight Reference Reference Reference Reference Reference
 Overweight −0.102 (−0.207, 0.003) 0.056 0.010 (−0.213, 0.232) 0.933 0.410 (0.174, 0.647) 0.001 0.021 (−0.144, 0.185) 0.805 0.338 (0.177, 0.498) <0.001
 Obese −0.236 (−0.399, −0.073) 0.005 0.017 (−0.328, 0.363) 0.921 0.902 (0.535, 1.268) <0.001 0.068 (−0.187, 0.322) 0.602 0.592 (0.343, 0.840) <0.001
 ΔBMI (per 1 kg/m2) −0.028 (−0.045, −0.010) 0.002 0.013 (−0.025, 0.050) 0.502 0.103 (0.063, 0.143) <0.001 0.011 (−0.016, 0.039) 0.424 0.093 (0.067, 0.120) <0.001
Model 2#
 Normal weight Reference Reference Reference Reference Reference
 Overweight −0.109 (−0.217, −0.001) 0.049 0.008 (−0.201, 0.217) 0.938 0.405 (0.164, 0.647) 0.001 0.024 (−0.143, 0.191) 0.776 0.333 (0.171, 0.496) <0.001
 Obese −0.231 (−0.399, −0.063) 0.007 0.011 (−0.312, 0.334) 0.947 0.832 (0.459, 1.206) <0.001 0.023 (−0.234, 0.281) 0.858 0.548 (0.297, 0.799) <0.001
 ΔBMI (per 1 kg/m2) −0.026 (−0.045, −0.008) 0.006 0.015 (−0.020, 0.051) 0.398 0.095 (0.054, 0.137) <0.001 0.008 (−0.020, 0.037) 0.573 0.090 (0.063, 0.117) <0.001