表 2. Comparison of clinical and metabolic parameters of subjects with different genotypes of APOC3 Sst Ⅰ polymorphism in GDM and control groups .
APOC3 基因 Sst Ⅰ多态性不同基因型亚组临床和代谢指标在GDM组和对照组的比较
| Parameter | GDM group | Control group | |||||
| S1S1 ( n=306) | S1S2 ( n=275) | S2S2 ( n=49) | S1S1 ( n=535) | S1S2 ( n=411) | S2S2 ( n=81) | ||
| * P<0.05, ** P<0.01, vs. S1S1 genotype carriers in the same group. | |||||||
| Delivery BMI/(kg/m 2) | 26.70±1.35 | 26.91±3.03 | 26.98±5.01 | 26.56±2.52 | 26.74±2.95 | 26.76±2.44 | |
| Fasting INS/(pmol/L) | 14.91±24.35 | 15.11±17.48 | 16.70±15.32 | 10.66±7.20 | 11.05±8.12 | 10.41±6.44 | |
| Fasting Glu/(mmol/L) | 4.65±0.89 | 4.58±0.72 | 4.63±0.74 | 4.40±0.80 | 4.39±0.61 | 4.37±0.50 | |
| HOMA-IR | 3.81±11.96 | 3.34±5.06 | 3.69±3.90 | 2.15±2.23 | 2.28±2.74 | 2.08±1.61 | |
| Triglycerides/(mmol/L) | 3.85±1.56 | 3.85±1.62 | 4.14±2.13 | 3.61±1.42 | 3.73±1.47 | 3.71±1.36 | |
| TC/(mmol/L) | 5.94±1.36 | 6.00±1.08 | 6.03±1.38 | 6.09±1.11 | 6.08±1.02 | 6.18±1.19 | |
| HDL-C/(mmol/L) | 1.93±0.42 | 2.03±0.46 ** | 2.11±0.42 ** | 1.98±0.42 | 2.03±0.40 | 2.00±0.42 | |
| LDL-C/(mmol/L) | 2.96±0.88 | 2.97±1.02 | 2.89±0.99 | 3.23±1.05 | 3.14±0.90 | 3.28±1.01 | |
| Atherogenic index | 2.14±0.55 | 2.03±0.54 * | 1.88±0.44 ** | 2.14±0.59 | 2.06±0.57 | 2.18±0.65 | |
| apoA1/(g/L) | 2.27±0.38 | 2.32±0.37 | 2.37±0.35 | 2.35±0.41 | 2.41±0.47 | 2.35±0.39 | |
| apoB/(g/L) | 1.15±0.25 | 1.16±0.25 | 1.13±0.31 | 1.16±0.27 | 1.15±0.26 | 1.17±0.27 | |
| apoB/apoA1 ratio | 0.52±0.13 | 0.51±0.13 | 0.49±1.50 | 0.51±0.15 | 0.49±0.14 | 0.51±0.14 | |