表 3. Clinical and metabolic parameters of obese and non-obese GDM subjects with different APOC3 gene Sst Ⅰ genotypes .

肥胖和非肥胖GDM孕妇 APOC3基因 Sst Ⅰ位点不同基因型亚组临床和代谢指标

Parameter	Overweight/Obese group				Non-obese group
	S1S1 ( n=217)	S1S2 ( n=201)	S2S2 ( n=32)		S1S1 ( n=89)	S1S2 ( n=74)	S2S2 ( n=17)
* P<0.05, ** P<0.01, vs. S1S1 genotype carriers in the same group; # P<0.01, vs. S1S2 genotype carriers in the same group.
Delivery BMI/(kg/m 2)	28.08±2.96	28.12±2.52	28.98±5.30		23.36±1.22	23.52±1.20	23.49±0.94
Fasting INS/(pmol/L)	16.03±27.32	15.88±18.43	20.17±17.63		12.32±15.10	13.10±14.87	9.58±5.87
Fasting Glu/(mmol/L)	4.68±0.93	4.62±0.75	4.53±0.66		4.58±0.79	4.49±0.63	4.77±0.87
HOMA-IR	4.24±13.99	3.57±5.59	4.43±4.55		2.80±4.55	2.72±3.21	2.15±1.63
Triglycerides/(mmol/L)	3.98±1.55	3.85±1.55	4.71±2.42 *, #		3.52±1.52	3.80±1.80	3.09±0.86
TC/(mmol/L)	5.82±1.04	5.96±1.13	6.13±1.56		6.25±1.90	6.12±0.93	5.92±0.97
HDL-C/(mmol/L)	1.89±0.39	2.01±0.45 **	2.05±0.42 *		2.03±0.49	2.11±0.47	2.22±0.41
LDL-C/(mmol/L)	2.87±0.84	2.93±0.87	2.86±1.07		3.19±0.95	3.07±1.35	3.00±0.83
Atherogenic index	2.14±0.52	2.03±0.54 *	1.99±0.45		2.14±0.64	1.98±0.53	1.70±0.35 **
apoA1/(g/L)	2.28±0.37	2.30±0.39	2.34±0.33		2.24±0.39	2.35±0.33	2.42±0.41
apoB/(g/L)	1.14±0.25	1.15±0.26	1.16±0.35		1.19±0.26	1.17±0.21	1.09±0.21
apoB/apoA1 ratio	0.51±0.12	0.51±0.14	0.50±0.16		0.54±0.14	0.50±0.11	0.46±0.12 *