Table 1.
Demographics, clinicopathologic characteristics and outcomes for the BR36 cohort (all enrolled patients)
| Characteristic | Number (%) |
|---|---|
| Sex | |
| Female | 26 (52.0) |
| Male | 24 (48.0) |
| Race | |
| White | 41 (82.0) |
| Black | 2 (4.0) |
| Asian | 4 (8.0) |
| Not Reported | 3 (6.0) |
| Agea | |
| <65 years | 22 (44.0) |
| ≥65 years | 28 (56.0) |
| ECOG PS | |
| 0 | 12 (24.0) |
| 1 | 38 (76.0) |
| Smoking status (current) | |
| Yes | 12 (24.0) |
| No | 37 (74.0) |
| Missing | 1 (2.0) |
| Smoking history | |
| >100 cigarettes during lifetime | 49 (98.0) |
| Missing | 1 (2.0) |
| Prior systemic therapy | |
| No | 46 (92.0) |
| Yes | 4 (8.0) |
| Prior radiation | |
| No | 27 (54.0) |
| Yes | 23 (46.0) |
| Prior surgery | |
| No | 1 (2.0) |
| Yes | 49 (98.0) |
| Stage | |
| Stage IIIb | 1 (2.0) |
| Stage IV | 49 (98.0) |
| Histology | |
| Adenocarcinoma | 38 (76.0) |
| Squamous cell carcinoma | 6 (12.0) |
| Other | 6 (12.0) |
| PD-L1 expression | |
| ≥50% TPS | 48 (96.0) |
| 1–49% | 2 (4.0) |
| RECIST response | |
| CR/PR | 16 (32.0) |
| SD/PD | 34 (68.0) |
| ctDNA response | |
| mR | 15 (42.9) |
| mPD | 20 (57.10) |
aMedian age was 65.5 years (range, 50–87 years).
bNot a candidate for surgical resection or definitive chemoradiation.