Table 3.
Effect sizes of BTM outcomes
| Time point | Intervention | Comparator | Studies | N | Hedges’ g [95%CI] | P value | I2 | Prediction interval1 | |
|---|---|---|---|---|---|---|---|---|---|
| Bone ALP | End intervention | EX + PT | PT | 3 | 379 | − 0.6758 [− 5.8782; 4.5266] | P = 0.6325 | 96.7% | [− 30.9090; 29.5574] |
| PINP | 3 months | EX + PT | PT | 2 | 73 | − 0.7434 [− 10.4164; 8.9297] | P = 0.5076 | 89.1% | NA |
| PINP | End intervention | EX + PT | PT | 2 | 73 | − 0.3927 [− 10.9450; 10.1595] | P = 0.7188 | 91.1% | NA |
| CTX-I | 3 months | EX + PT | PT | 2 | 73 | − 0.6890 [− 9.6091; 8.2310] | P = 0.5059 | 87.4% | NA |
| CTX-I | End intervention | EX + PT | PT | 2 | 73 | − 0.0405 [− 7.0467; 6.9657] | P = 0.9533 | 81.1% | NA |
EX exercise training, PT pharmacological therapy, 95%CI 95% confidence intervals, NA not available
1The prediction interval indicates the heterogeneity in the data and the range of potential values that could be possible in future studies