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. 2023 Sep 6;27(10):2177–2186. doi: 10.1007/s11605-023-05820-8

Table 3.

Factors associated with cumulative major complications (death, sepsis, admission to ICU)

NOT major complications N 340 Major complications N 84 Univariate p value Odds ratio [95% interval] Multiv. p value
CFS 1–6 242 (71.2%) 38 (45.2%)
CFS 7–9 98 (28.8%) 46 (54.8%)
CFS value 6 [5–7] 6 [6–7] 0.002 1.41 [1.13–1.75] 0.002
Age 85 [82–89] 85 [81–91] 0.485
Sex (Male) 134 (40.5%) 51 (54.8%) 0.014 1.67 [1.03–2.71] 0.038
ED presentation
Fever 47 (13.8%) 16 (19.0%) 0.228
Abdominal pain 235 (69.1%) 46 (54.8%) 0.013 0.69 [0.42–1.13] 0.141
Vomit 171 (50.3%) 38 (45.2%) 0.407
Gastrointestinal bleeding 17 (5.0%) 5 (6.0%) 0.725
Perforation 12 (3.5%) 4 (4.8%) 0.596
Treatment
Medical treatment 205 (61.9%) 41 (44.1%) 0.471
Percutaneous procedures 11 (3.3%) 7 (7.5%) 0.005
Ostomy 39 (11.5%) 17 (20.2%) 0.034
Surgery (overall) 124 (36.5%) 36 (42.9%) 0.012 1.91 [1.17–3.12] 0.010
Comorbidities
CCI 6 [4–8] 7 [5–9] 0.045 0.97 [0.86–1.09] 0.649
History of CAD 43 (12.6%) 17 (20.2%) 0.074
CHF 33 (9.7%) 12 (14.3%) 0.222
Cerebrovascular disease 24 (7.1%) 8 (9.5%) 0.440
Dementia 35 (10.3%) 15 (17.9%) 0.054
COPD 48 (14.1%) 10 (11.9%) 0.597
Diabetes 31 (9.1%) 17 (20.2%) 0.004
Chronic kidney disease 55 (16.2%) 12 (14.3%) 0.671
Oncological disease 127 (37.4%) 43 (46.4%) 0.127
Metastatic cancer 47 (13.8%) 17 (20.2%) 0.141
Aetiology
Malignancy 88 (25.9%) 32 (38.1%) 0.026 1.53 [0.78–2.97] 0.213
Non malignant 90 (27.2%) 15 (16.1%) 0.029
(i) Surgical Adhesions 56 (16.5%) 5 (6.0%) 0.014
(ii) Hernia 31 (9.1%) 4 (4.8%) 0.194
(iii) Volvulus 16 (4.7%) 3 (3.6%) 0.653

Abbreviations: CCI, Charlson comorbidity index; CFS, Clinical Frailty Scale; CAD, coronary artery disease; CHF, chronic heart failure; COPD, chronic obstructive pulmonary disease