Table 2.
Condition | Reviews | RCTs* | Participants† | Standardised mean difference | ||
25th percentile | Median | 75th percentile | ||||
Arthritis | 4 | 55 | 3713 | –0.73 | –0.40 | –0.31 |
Cancer | 17 | 196 | >14 616 | –0.46 | –0.22 | –0.15 |
Blood | 2 | 5 | 315 | –0.25 | –0.24 | –0.22 |
Breast | 8 | 84 | 7113 | –0.61 | –0.47 | –0.17 |
Colorectal | 3 | 8 | 575 | –0.23 | –0.21 | –0.11 |
Lung | 1 | 6 | 695 | –0.49 | ||
Lymphoma | 1 | 2 | 161 | –0.35 | ||
Non-specific | 5 | 85 | >5543 | –0.22 | –0.21 | –0.13 |
Prostate | 2 | 4 | 214 | –0.20 | –0.18 | –0.16 |
Chronic disease | 3 | 18 | >994 | –0.38 | –0.27 | –0.27 |
Chronic obstructive pulmonary disease | 2 | 16 | 1175 | –0.86 | –0.72 | –0.58 |
Cardiovascular disease | 5 | 54 | 6681 | –0.37 | –0.16 | –0.14 |
Stroke | 2 | 19 | 1580 | –0.36 | –0.25 | –0.13 |
Heart disease | 3 | 26 | 4435 | –0.33 | –0.16 | –0.15 |
Dementia | 4 | 37 | >3470 | –0.37 | –0.27 | –0.11 |
Diagnosed | 3 | 16 | >881 | –0.41 | –0.31 | –0.06 |
Cognitive impairment | 1 | 21 | 2589 | –0.23 | ||
Depression | 15 | 299 | >13 318 | –0.82 | –0.62 | –0.33 |
Diagnosed | 14 | 273 | >12 953 | –0.96 | –0.66 | –0.38 |
Symptoms | 3 | 26 | >365 | –0.74 | –0.56 | –0.34 |
General population | 9 | 208 | >14 145 | –0.69 | –0.62 | –0.35 |
Adults | 6 | 99 | >9016 | –0.82 | –0.69 | –0.66 |
Older adults | 3 | 75 | >4862 | –0.52 | –0.36 | –0.28 |
HIV/AIDS | 1 | 9 | 395 | –0.84 | ||
Kidney disease | 3 | 11 | 567 | –1.14 | –0.85 | −0.71 |
Mental health disorders | 6 | 39 | 2083 | –0.49 | –0.44 | –0.37 |
Fatigue | 1 | 7 | 415 | –0.58 | ||
Non-specific | 1 | 13 | 362 | –0.41 | ||
Post-traumatic stress disorder | 2 | 7 | 332 | –0.49 | –0.43 | –0.37 |
Schizophrenia | 1 | 3 | 94 | –0.26 | ||
Substance abuse | 1 | 9 | 610 | –0.47 | ||
Neurological disease | 4 | 62 | 2901 | –0.46 | –0.37 | –0.32 |
Multiple sclerosis | 3 | 39 | 1577 | –0.51 | –0.37 | –0.36 |
Non-specific | 1 | 23 | 1324 | –0.28 | ||
Pregnancy/postpartum | 3 | 43 | 3364 | –0.63 | –0.59 | –0.40 |
Pregnant | 1 | 10 | 609 | –0.59 | ||
Postpartum | 2 | 33 | 2755 | –0.69 | –0.49 | –0.34 |
*Reviews may have included overlapping randomised controlled trials.
†Randomised controlled trials may have included overlapping participants.
RCTs, randomised controlled trials.