Table 3.

The experimental data of sitagliptin phosphate solubility in SC-CO2 based on distinct conditions (temperatures (T) and pressures (P) for binary system).

Temperaturea (K)	Pressurea (MPa)	Densityb (kg m−3)	y × 104 (mole fraction)	Standard deviation × (105)	Expanded uncertainty of mole fraction (104 U)	S (Solubility (g l−1))
308	12	768.42	0.302	0.040	0.101	0.267
	15	816.06	0.337	0.056	0.131	0.316
	18	848.87	0.359	0.072	0.162	0.350
	21	874.4	0.387	0.090	0.197	0.389
	24	895.54	0.441	0.118	0.253	0.454
	27	913.69	0.477	0.154	0.323	0.500
	30	929.68	0.517	0.172	0.360	0.552
318	12	659.73	0.271	0.036	0.091	0.206
	15	743.17	0.352	0.059	0.138	0.301
	18	790.18	0.395	0.079	0.177	0.358
	21	823.7	0.449	0.145	0.304	0.424
	24	850.1	0.506	0.067	0.169	0.494
	27	872.04	0.530	0.100	0.227	0.531
	30	890.92	0.583	0.117	0.263	0.596
328	12	506.85	0.239	0.056	0.122	0.139
	15	654.94	0.333	0.070	0.156	0.250
	18	724.13	0.426	0.085	0.191	0.355
	21	768.74	0.494	0.137	0.292	0.436
	24	801.92	0.551	0.147	0.315	0.507
	27	828.51	0.586	0.176	0.372	0.557
	30	850.83	0.651	0.217	0.454	0.636
338	12	384.17	0.207	0.028	0.070	0.092
	15	555.23	0.303	0.051	0.119	0.193
	18	651.18	0.456	0.091	0.205	0.341
	21	709.69	0.553	0.074	0.186	0.451
	24	751.17	0.609	0.102	0.239	0.525
	27	783.29	0.635	0.127	0.285	0.571
	30	809.58	0.698	0.163	0.356	0.649

^aStandard uncertainty u are u(T) =  ± 0.1 K; u(p) =  ± 1 bar. Also, relative standard uncertainties are obtained below 5% for mole fractions and solubilities. The value of the coverage factor k = 2 was chosen on the basis of the level of confidence of approximately 95 percent.

^bData from the Span–Wagner equation of state⁶².