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. 2023 Oct 16;13:17560. doi: 10.1038/s41598-023-44753-9

Table 2.

Antimicrobial activity assessment of compounds 717 using agar diffusion technique.

Compound Inhibition zones diameter (mm)
B. mycoides E. coli C. albicans
7 36 ± 1.25 30 ± 0.74 37 ± 1.20
8 37 ± 0.23 29 ± 0.44 38 ± 0.67
9 41 ± 0.0 37 ± 0.74 41 ± 0.21
10 24 ± 0.87 22 ± 0.39 21 ± 0.32
11 31 ± 0.52 27 ± 0.58 32 ± 0.17
13 16 ± 0.41 18 ± 1.84 18 ± 0.66
14 15 ± 0.25 17 ± 0.81 17 ± 0.27
15 23 ± 0.35 24 ± 0.68 24 ± 1.22
16 16 ± 0.97 16 ± 0.35 16 ± 0.95
17 18 ± 0.0 16 ± 0.54 15 ± 0.42
DMSO (control) 0 0 0
Colstin 10 mcg 0 0 0
Tobramycin 10 mcg 10 ± 0.31 13 ± 0.22 12 ± 0.61
Gentamicin 10 mcg 11 ± 0.43 12 ± 0.18 12 ± 0.89
Ampicillin 10 mcg 12 ± 0.93 20 ± 1.05 14 ± 0.25
Erythromycin 15 mcg 17 ± 0.15 29 ± 2.13 25 ± 0.00

Significant values are in italics.

200 μL of dissolved compounds (10 mg/mL) in DMSO were applied to 15 mm holes prepared in the inoculated agar plates. Culture plates were incubated overnight at 37 °C.