Table 2.
Antimicrobial activity assessment of compounds 7–17 using agar diffusion technique.
| Compound | Inhibition zones diameter (mm) | ||
|---|---|---|---|
| B. mycoides | E. coli | C. albicans | |
| 7 | 36 ± 1.25 | 30 ± 0.74 | 37 ± 1.20 |
| 8 | 37 ± 0.23 | 29 ± 0.44 | 38 ± 0.67 |
| 9 | 41 ± 0.0 | 37 ± 0.74 | 41 ± 0.21 |
| 10 | 24 ± 0.87 | 22 ± 0.39 | 21 ± 0.32 |
| 11 | 31 ± 0.52 | 27 ± 0.58 | 32 ± 0.17 |
| 13 | 16 ± 0.41 | 18 ± 1.84 | 18 ± 0.66 |
| 14 | 15 ± 0.25 | 17 ± 0.81 | 17 ± 0.27 |
| 15 | 23 ± 0.35 | 24 ± 0.68 | 24 ± 1.22 |
| 16 | 16 ± 0.97 | 16 ± 0.35 | 16 ± 0.95 |
| 17 | 18 ± 0.0 | 16 ± 0.54 | 15 ± 0.42 |
| DMSO (control) | 0 | 0 | 0 |
| Colstin 10 mcg | 0 | 0 | 0 |
| Tobramycin 10 mcg | 10 ± 0.31 | 13 ± 0.22 | 12 ± 0.61 |
| Gentamicin 10 mcg | 11 ± 0.43 | 12 ± 0.18 | 12 ± 0.89 |
| Ampicillin 10 mcg | 12 ± 0.93 | 20 ± 1.05 | 14 ± 0.25 |
| Erythromycin 15 mcg | 17 ± 0.15 | 29 ± 2.13 | 25 ± 0.00 |
Significant values are in italics.
200 μL of dissolved compounds (10 mg/mL) in DMSO were applied to 15 mm holes prepared in the inoculated agar plates. Culture plates were incubated overnight at 37 °C.