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. 2023 Oct 16;13:17516. doi: 10.1038/s41598-023-44629-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Analysis of hypoxic vs. normoxic groups in male mice. (A) Represents the volcano plot with 2FC and a p-value < 0.05, (B) represents the Orthogonal Partial Least Square Analysis between the hypoxic male and normoxic male group. (C) The pathway analysis. (D) Represents the heatmap of the top 25 significant features between the male hypoxic and male normoxic groups; log normalized intensity is presented in the red-blue colors, where red represents high, and blue indicates low expressions.