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. 2023 Jul 25;72(11):2112–2122. doi: 10.1136/gutjnl-2023-330291

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Roseburia intestinalis (R.i) enhances epithelial barrier functions in Apc^Min/+ mice. (A) FITC-dextran (4 kDa) concentration (ng/mL) in Apc^Min/+ mice serum. (B) Expression levels of tight junction proteins ZO-1 and claudin-3 determined by western blot analysis in colon tissues of Apc^Min/+ mice. (C) Representative ZO-1 and claudin-3 immunohistochemistry staining images (scale bar=50 µm). Con, control; E. coli, Escherichia coli; FITC, fluorescein isothiocyanate; ZO-1, zonula occludens-1.