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. 2023 May 16;60(10):965–973. doi: 10.1136/jmg-2022-109132

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Awake EEG studies of individuals 5 and 8. Longitudinal bipolar montage at sensitivity 70 μV/cm is shown in all the cases. Individual 5: while EEG at 14 months old during his first seizures showed a slow and low voltage background activity without epileptic abnormalities (A1), the EEG at the age of 2 years, during wakefulness with eyes closed, showed a slow background activity without epileptiform abnormalities (A2). Individual 8: EEGs at the age of 13 years, during wakefulness with eyes closed (B1) and eyes open (B2) showed normal background activity, with epileptic abnormalities (sharp waves and spikes) in bilateral frontocentrotemporal region.