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. 2023 Jun 8;109(20):1542–1549. doi: 10.1136/heartjnl-2023-322459

Table 3.

HRs and 95% CIs for the association of BMI categories with all-cause mortality among people with heart failure

BMI category N n Crude model Age and sex adjusted N* n* Multivariable model†
Underweight (<18.5 kg/m2) 1084 756 1.59 (1.48 to 1.71) 1.52 (1.41 to 1.64) 681 446 1.59 (1.45 to 1.75)
Healthy weight (18.5–25 kg/m2) 14 880 8959 1.00 (Reference) 1.00 (Reference) 10 223 5579 1.00 (Reference)
Overweight (25–30 kg/m2) 17 277 8939 0.74 (0.72 to 0.76) 0.81 (0.79 to 0.84) 13 071 6054 0.78 (0.75 to 0.81)
Obesity class I (30–35 kg/m2) 9013 4197 0.64 (0.62 to 0.66) 0.79 (0.76 to 0.82) 7235 3045 0.76 (0.73 to 0.80)
Obesity class II (35–40 kg/m2) 3400 1417 0.56 (0.53 to 0.59) 0.78 (0.74 to 0.82) 2904 1123 0.76 (0.71 to 0.81)
Obesity class III (≥40 kg/m2) 1877 745 0.56 (0.52 to 0.60) 0.95 (0.88 to 1.02) 1614 594 0.96 (0.88 to 1.05)

*The numbers at risk and dying are smaller in the multivariable model due to missing data.

†Adjusted for sex, age, smoking status, index of multiple deprivation, ethnicity, systolic and diastolic blood pressure, total cholesterol, and history of atrial fibrillation, angina, type 2 diabetes mellitus, hypertension, ischaemic heart disease, myocardial infarction, stroke, valvular heart disease and other cardiovascular diseases.

BMI, body mass index; N, number at risk of dying within the relevant BMI category; n, number dying from all-causes for the BMI category.