Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Oct 3;14:1258796. doi: 10.3389/fmicb.2023.1258796

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Sutton, Nash, Sives, Borowska, Mitchell, Vohra, Stevens and Vervelde.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

WT STm infection remodels F-actin in chicken enteroids. Confocal micrographs showing F-actin remodeling in (A) WT STm infected 2D and 3D enteroids. At 4 hpi, dense F-actin staining can be observed surrounding the invading bacteria consistent with reorganization of subcortical actin stimulating membrane ruffling (white arrows). By 8 hpi, numerous bacteria can be observed within epithelial cells. At 8 hpi the number of internalized bacteria was markedly higher in 3D enteroids inoculated with the same bacterial dose. (B) No F-actin remodeling was observed in ΔprgH STm infected 2D and 3D enteroids at 8 hpi, although bacteria were observed in close association with the apical surface of epithelial cells. Images are representative of 3 independent experiments. Scale bars = 100 μm and 50 μm.