TABLE 3.
Advantages/disadvantages of conductive polymers used for skeletal muscle regeneration.
Conductive polymer | Advantages | Disadvantages | Citations |
---|---|---|---|
Polyaniline (PANi) | Better differentiation of tissue when added to copolymers Improved differentiation More and longer myotubes in PANi-containing scaffolds |
Slightly cytotoxic No effect on cell adhesion and proliferation Brittle |
Green et al. (2008), Kim et al. (2009a), Liu et al. (2010), Guo and Ma (2018) |
Polypyrrole | Supports cell proliferation and differentiation Increases conductivity of scaffold without decreasing metabolic activity of cells |
Low strength Brittle |
Green et al. (2008), Guo and Ma (2018), Basurto et al. (2021), Bilge et al. (2021) |
Polythiophene | Easily modifiable Soluble in organic solvents |
Addition of polythiophene reduces Young’s modulus Low elasticity Brittle |
Green et al. (2008), Jaymand et al. (2016), Guo and Ma (2018), Massoumi et al. (2021) |