Table 2. Adverse event.

Adverse events	Grade 1, n (%)	Grade 2, n (%)	Grade 3, n (%)
Paresthesia	37 (35.9)	19 (18.4)	2 (1.9)
Muscle cramping	22 (21.4)	2 (1.9)	–
Rash	18 (17.5)	9 (8.7)	2 (1.9)
Bilirubin elevation	–	–	1 (1.0)
Diarrhea	15 (14.6)	2 (1.9)	–
Pruritus	13 (12.6)	5 (4.9)	–
Headache	10 (9.7)	3 (2.9)	–
Fatigue	6 (5.8)	6 (5.8)	–
Anorexia	4 (3.9)	5 (4.9)	–
Nausea	5 (4.9)	2 (1.9)	–
Dizziness	6 (5.8)	1 (1.0)	–
Edema	4 (3.9)	1 (1.0)	–
Nail change	3 (2.9)	1 (1.0)	–
Mucositis	3 (2.9)	1 (1.0)	–
Pneumonitis	1 (1.0)	1 (1.0)	–
Myalgia	7 (6.8)	–	–
AST/ALT elevation	2 (1.9)	–	–

AST, aspartate aminotransferase; ALT, alanine aminotransferase.