Table II. In vitro potency of ustekinumab and guselkumab on cytokine production.

	IC50 (nM)
Cytokine	GUS	UST	Increased Potency of GUSa
IL-17A	0.10	0.38	3.8
IL-17F	0.11	0.49	4.5
IL-22	0.09	0.40	4.4

^aUST IC₅₀:GUS IC₅₀.

GUS, guselkumab; UST, ustekinumab.