Table 6. Objectives, formulated outcome measures and how these were met.

Objectives	Outcome Measures	Result
Primary: To develop, implement and assess a hospital-based system for patient-centred surveillance of Drug Resistant Infections	A protocol and guideline for implementation of this system for further roll-out in other sites	Feedback was collected during the pilot and on post pilot assessment and was used to update the protocol
Secondary: To systematically characterize drug-resistant infections based on important clinical syndromes, to adequately inform treatment guidelines To implement clinical syndrome-guided diagnostic stewardship of patients with suspected infection To determine the duration, cost of hospitalisation and patient outcome of DRI and non-DRI	Antimicrobial susceptibility data with both pathogen and clinical denominators, including predefined subgroups Proportion of timely and correctly sampled patients per syndrome Antimicrobial susceptibility data, cost estimates, 28-day mortality data	Collection and combination of clinical and microbiological data was feasible (all secondary objectives), subgroup analysis showed clear differences by antibiotic use and origin of infection Data were collected and used for real-time feedback and further development of protocol Data were collected and shown
Tertiary: To evaluate the feasibility and acceptability of the surveillance system and package of tools	Results of clinician and laboratory technician surveys	Feedback was collected using before and after surveys and results were used to update the protocol