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. 2023 Oct 11;59:334–356. doi: 10.1016/j.jdsr.2023.09.003

Table 1.

Structured PICOS.

P (Population) Oropharyngeal fluids from COVID-19 positive patients or surrogates COVID-19 positive patients
I (Intervention) Exposure to oral antiseptics Rinsing with oral antiseptics
C (Comparison) Control solutions Control solutions
O (Outcome) SARS-CoV-2 load reduction in the samples SARS-CoV-2 load reduction in the saliva
S (Study) In vitro studies Human clinical studies