Table 3.
HR (95% CIs) for all-cause and cause-specific mortality according to serum 25(OH)D concentrations among participants with kidney stones.
| Serum 25(OH)D concentrations (nmol/L) | P for trend | ||||
|---|---|---|---|---|---|
| <25 | 25-49.9 | 50-74.9 | ≥75 | ||
| All-cause mortality | |||||
| Number of deaths (%) Model 1 HR (95% CI) P Model 2 HR (95% CI) P Model 3 HR (95% CI) P |
19 (19.2) Reference Reference Reference |
79 (11.8) 0.58 (0.35, 0.95) 0.03 0.56 (0.32, 0.99) 0.04 0.62 (0.34, 1.13) 0.12 |
142 (12.9) 0.65 (0.40, 1.05) 0.08 0.60 (0.34, 1.03) 0.06 0.63 (0.35, 1.13) 0.12 |
135 (12.9) 0.69 (0.43, 1.12) 0.13 0.50 (0.29, 0.87) <0.01 0.48 (0.26, 0.87) 0.02 |
0.68 0.04 0.02 |
| CVD mortality | |||||
| Number of deaths (%) Model 1 HR (95% CI) P Model 2 HR (95% CI) P Model 3 HR (95% CI) P |
7 (7.1) Reference Reference Reference |
20 (3.0) 0.96 (0.40, 2.31) 0.92 0.84 (0.28, 2.52) 0.76 0.55 (0.16, 1.95) 0.36 |
32 (2.9) 0.59 (0.25, 1.38) 0.23 0.52 (0.17, 1.61) 0.25 0.21 (0.05, 0.85) 0.03 |
24 (2.3) 1.21 (0.51, 2.85) 0.67 1.29 (0.40, 4.21) 0.67 0.91 (0.23, 3.63) 0.89 |
0.58 0.27 0.68 |
| Cancer mortality | |||||
| Number of deaths (%) Model 1 HR (95% CI) P Model 2 HR (95% CI) P Model 3 HR (95% CI) P |
7 (7.1) Reference Reference Reference |
13 (2.0) 0.76 (0.21, 2.70) 0.67 0.68 (0.12, 3.72) 0.65 0.67 (0.12, 3.78) 0.65 |
20 (1.8) 0.45 (0.13, 1.58) 0.21 0.23 (0.05, 1.02) 0.05 0.33 (0.07, 3.78) 0.64 |
39 (3.7) 0.45 (0.13, 1.52) 0.20 0.20 (0.05, 0.82) 0.03 0.32 (0.07, 1.42) 0.13 |
0.08 0.02 0.08 |
Model 1: Non-adjusted model.
Model 2: Adjusted for age, gender, race, BMI, educational attainment, leisure-time physical activity, marital status, family poverty ratio, smoking status, and alcohol status.
Model 3: Adjusted for age, gender, race, BMI, educational attainment, leisure-time physical activity, marital status, family poverty ratio, smoking status, alcohol status, diabetes, hypertension, stroke chronic kidney disease, cancer, and cardiovascular disease.