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. 2023 Oct 16;6(10):e2337889. doi: 10.1001/jamanetworkopen.2023.37889

Table 1. Clinicopathologic Characteristics of 620 Patients With 622 Nodules.

Characteristics Patients or nodules, No. (%)
Sex
Female 442 (71.3)
Male 178 (28.7)
Age, mean (SD), y 53.5 (12.0)
Smoking history, ever 102 (16.5)
Operative procedure
Lobectomy 121 (19.5)
Segmentectomy 179 (28.8)
Wedge resection 322 (51.7)
Tumor location
LUL 158 (25.4)
LLL 96 (15.4)
RUL 216 (34.7)
RML 43 (7.0)
RLL 109 (17.5)
Radiologic parameters
Radiologic tumor size, mm
≤10 224 (36.0)
10 to ≤20 311 (50.0)
>20 87 (14.0)
Solid component size, median (range), mm 2.5 (0-26.0)
Shape
Round/oval 244 (39.2)
Polygonal/irregular 378 (60.8)
Margin
Smooth 244 (39.2)
Lobulated/spiculated 378 (60.8)
Tumor-lung interface
Clear 476 (76.5)
Unclear 146 (23.5)
Bubble lucency
Absent 267 (42.9)
Present 355 (57.1)
Air bronchogram
Absent 313 (50.3)
Present 309 (49.7)
Pleural indentation
Absent 409 (65.8)
Present 213 (34.2)
Pathologic characteristics
Pathological diagnosis
AIS 47 (7.6)
MIA 342 (55.0)
IAD 233 (37.4)
Histological predominant subtypes
LPA 48 (20.6)
APA 130 (55.8)
PPA 52 (22.3)
MPA 0 (0)
SPA 1 (0.4)
IMA 2 (0.9)
Pathologic tumor size, median (range), mm 10.0 (3.0-35.0)
Pathological stage
0 47 (7.5)
IA1 382 (61.4)
IA2 141 (22.7)
IA3 19 (3.1)
IB 33 (5.3)

Abbreviations: AIS, adenocarcinoma in situ; APA, acinar predominant adenocarcinoma; IAD, invasive adenocarcinoma; IMA, invasive mucinous adenocarcinoma; LLL, left lower lobe; LPA, lepidic predominant adenocarcinoma; LUL, left upper lobe; MIA, minimally invasive adenocarcinoma; MPA, micropapillary predominant adenocarcinoma; PPA, papillary predominant adenocarcinoma; RLL, right lower lobe; RML, right middle lobe; RUL, right upper lobe; SPA, solid predominant adenocarcinoma.