| Methods |
Randomised controlled trial |
| Participants |
Children under 2 years of age with clinical suspected bronchiolitis |
| Interventions |
IV ampicillin (parenteral ampicillin 50 mg/kg/6‐hourly + supportive care), oral erythromycin (oral erythromycin 10 mg/kg 6‐hourly + supportive care), control |
| Outcomes |
Respiratory rate, oxygen saturation, wheeze, fever, length of hospital stay, shortness of breath |
| Notes |
― |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
Random number table |
| Allocation concealment (selection bias) |
Unclear risk |
Not described |
| Blinding (performance bias and detection bias)
All outcomes |
High risk |
Seems unlikely, not described |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
32 participants dropped out (10%), 17 were referred to paediatric intensive care and 15 withdrew from the study or left the recruiting hospitals |
| Selective reporting (reporting bias) |
High risk |
|
| Other bias |
Low risk |
Bangladesh Medical Research Council funded this project (through a grant from the World Bank) |
