Comparison 1. Systemic antibiotic given according to sensitivities versus standard care.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Complete healing at 3 weeks	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	0.62 [0.22, 1.72]
2 Complete healing—eventual, assessment point not stated	1	56	Risk Ratio (M‐H, Fixed, 95% CI)	0.91 [0.66, 1.25]
3 Bacterial eradication	1	48	Risk Ratio (M‐H, Fixed, 95% CI)	1.6 [0.61, 4.19]