Table 2.

Ability of the pinching features (aggregated by median) to differentiate and distinguish between HCs^a and people with MS^b subgroups^c.

Feature	HCs vs people with MS-Normal			HCs vs people with MS-Abnormal			People with MS-Normal vs people with MS-Abnormal
	P valued	AUCe	Cohen d	P valued	AUC	Cohen d	P valued	AUC	Cohen d
Number of performed pinches	.76	0.53	0.09	.14	0.67	0.72	.02 f	0.70	0.76
Number of successful pinches	.81	0.52	0.22	.06	0.71	0.66	.01	0.75	0.98
Successful attempts fraction	.61	0.56	0.28	.47	0.59	0.35	.08	0.66	0.67
Two-finger attempts fraction	.41	0.60	0.35	.02	0.75	0.35	.02	0.70	0.91
Pinch time	.61	0.56	0.07	.47	0.58	0.36	.04	0.68	0.43
Gap time	.47	0.58	0.35	.02	0.75	0.79	.03	0.69	0.71
Double touch asynchrony	.74	0.54	0.22	.02	0.75	0.78	<.001	0.78	1.04
Double lift asynchrony	.87	0.52	0.33	.47	0.58	0.08	.41	0.59	0.39
First points distance	.75	0.54	0.06	.62	0.56	0.28	.41	0.59	0.33
Last points distance	.26	0.63	0.53	.47	0.59	0.32	.02	0.73	0.86
Finger path length	.47	0.58	0.42	.74	0.54	0.25	.23	0.62	0.37
Finger velocity	≥.99	0.50	0.02	.47	0.59	0.41	.34	0.60	0.40
Finger path ratio	.47	0.58	0.44	.41	0.61	0.29	.02	0.72	0.93

^aHC: healthy control.

^bMS: multiple sclerosis.

^cThis analysis included 18 HCs, 38 people with MS–Normal (ie, with a baseline Nine-Hole Peg Test time below 22.15 seconds), and 29 people with MS-Abnormal (ie, with a baseline Nine-Hole Peg Test time above 22.15 seconds).

^dMann-Whitney U test with false discovery rate correction adjusted for age and sex.

^eAUC: area under the curve.

^fItalic formatting represents a statistically significant P value of <.05.