Table 5.

Ability of the fatigability features (aggregated by SD) to differentiate and distinguish between HCs^a and people with MS^b subgroups^c.

Feature	HCs vs people with MS-Normal			HCs vs people with MS-Abnormal			People with MS-Normal vs people with MS-Abnormal
	P valued	AUCe	Cohen d	P valued	AUC	Cohen d	P valued	AUC	Cohen d
Fatigability number of performed pinches	.87	0.52	0.00	.55	0.59	0.39	.43	0.59	0.39
Fatigability number of successful pinches	.94	0.51	0.08	.72	0.55	0.18	.74	0.54	0.07
Fatigability successful attempts fraction	.72	0.55	0.32	.03 f	0.74	0.63	<.001	0.77	1.10
Fatigability two-finger attempts fraction	.94	0.51	0.03	.03	0.74	0.64	.01	0.75	0.71
Fatigability pinch time	.72	0.55	0.40	.23	0.65	0.24	.03	0.71	0.37
Fatigability gap time	.78	0.54	0.06	.32	0.63	0.49	.16	0.64	0.46
Fatigability double touch asynchrony	.94	0.51	0.31	.02	0.76	0.52	<.001	0.82	0.76
Fatigability double lift asynchrony	.89	0.52	0.33	.20	0.66	0.21	.07	0.67	0.28
Fatigability first points distance	.72	0.56	0.18	.67	0.57	0.33	.18	0.64	0.52
Fatigability last points distance	.72	0.55	0.49	.63	0.58	0.15	.20	0.63	0.57
Fatigability finger path length	.72	0.55	0.43	.52	0.60	0.36	.03	0.70	0.75
Fatigability finger velocity	.87	0.52	0.24	.55	0.59	0.40	.67	0.56	0.22
Fatigability finger path ratio	.62	0.58	0.43	.51	0.60	0.32	.06	0.68	0.47

^aHC: healthy control.

^bMS: multiple sclerosis.

^cThis analysis included 18 HCs, 38 people with MS–Normal (ie, with a baseline Nine-Hole Peg Test time below 22.15 seconds), and 29 people with MS-Abnormal (ie, with a baseline Nine-Hole Peg Test time above 22.15 seconds).

^dMann-Whitney U test with false discovery rate correction adjusted for age and sex.

^eAUC: area under the curve.

^fItalic formatting represents a statistically significant P value at <.05.