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. 2023 Oct 17;13(43):30499–30510. doi: 10.1039/d3ra06191d

Analytical figure of merit of various detection methods of MDA.

Method Nanoprobe, nanopolymer LOD/LOQ/LLOQ Samples Ref.
SERS 4-Aminothiophenol (4-ATP)-modified Au nanoflowers (Au NFs) probes ∼3.6 × 10−13 M Human serum 54
Fluorescence spectroscopy MDA (MDAP-1) 0.6 mM Living cell 55
Fluorescence spectroscopy (Mito-FMP) based on a benzoxadiazole platform Not reported Hela cells 56
Electropolymerization PARG-GQDs-CS 5.94 nM Breath samples 57
Spectrophotometric DES smart labels Not reported Real samples (fried seed oil) 58
SERS 4-Aminophenylthiophenol (PATP) 0.50 μM Blood samples 59
UV-Vis/fluorescence 4-Hydrazinyl-7-nitrobenzofurazan (NBDH) The MDA detection range of our probe NBDH falls between 0.1 and 20 μM, and the corresponding detection limit amounts to 7.2 nM Serum samples 60
Electrochemical sensing Polymer (MGO@MIPy) 0.01 μM Chicken serum samples 61
Colorimetric and spectrophotometric chemosensor AgNPrs probe 0.12 μM Urine, EBC This work