Table 3.
Effect of 8-week garlic supplementation on androgens and glycemic-related markers
| Variables | Intervention (n=40) | P* | Placebo (n=40) | P* | P** | ||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| Before | After | Change | Before | After | Change | ||||
| Testosterone | 0.70±0.27 | 0.63±0.37 | -0.07±0.41 | 0.32 | 0.58±0.41 | 0.65±0.44 | 0.06±0.32 | 0.22 | 0.190 |
| Sex hormone-binding globulin (SHBG) | 48.93±35.26 | 59.50±54.14 | 10.56±44.90 | 0.17 | 72.51±79.89 | 68.80±59.47 | -3.71±46.52 | 0.64 | 0.241 |
| Free androgen index (FAI) | 2.42±2.31 | 1.78±1.54 | -0.63±2.48 | 0.13 | 1.33±1.26 | 1.54±1.40 | 0.20±0.71 | 0.10 | 0.097 |
| Fasting plasma glucose | 92.92±6.74 | 89.70±5.40 | -3.22±7.41 | 0.009 | 90.25±7.51 | 90.97±4.67 | 0.72±5.37 | 0.399 | 0.008 |
| Fasting insulin | 12.88±7.08 | 12.22±5.67 | -0.65±6.01 | 0.497 | 12.23±5.64 | 13.49±5.41 | 1.25±5.01 | 0.122 | 0.074 |
| HOMA-ir | 2.99±1.75 | 2.69±1.23 | -0.29±1.45 | 0.208 | 2.76±1.36 | 3.05±1.27 | 0.28±1.20 | 0.145 | 0.028 |
| QUICKI | 0.33±0.02 | 0.33±0.02 | 0.001±0.2 | 0.789 | 0.32±0.02 | 0.33±0.03 | -0.007±0.02 | 0.045 | 0.062 |
Data are presented as mean±SD. *Paired sample Student’s t-test. **obtained from ANCONA test, adjusted for age, BMI, energy intake, physical activity, and baseline