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The fetal inflammatory response syndrome (FIRS) is associated with multi-systemic involvement. Clinical and/or experimental evidence suggests that there is involvement of the organs displayed in the figure. The data to support this conclusion is reviewed in the article. (Modified with permission from Gotsch F, Romero R, Kusanovic JP, Mazaki-Tovi S, Pineles B, Erez O, Espinoza J, Hassan SS. Fetal Inflammatory Response Syndrome. Clinical Obstetrics and Gynecology 50:652–683; 2007).
